Imaging Genetics is the study of how individual genetic differences lead to differences in brain wiring, structure, and intellectual function. Here at the Imaging Genetics Center, led by Paul Thompson, we investigate how genes and environment affect the brain. We co-founded a worldwide imaging genetics consortium, called the ENIGMA Consortium, which is making rapid progress discovering genetic variants that affect brain integrity. At last count, ENIGMA brings together more than 700 co-authors from 300 institutions, to analyze genome-wide scans and MRI scans from 50,000+ people. Here, we see the results of one such ENIGMA study, showing the effects of rs945270 (a SNP) on putamen shape. This and results like it help us understand how brain variation and disease risk relate to variations in our genome. IGC also directs several mathematical and technical projects to improve the methods used in these joint genetic/image analyses.