Autism Risk Gene
Healthy individuals who carry a gene variation linked to an increased risk of autism have structural differences in their brains that may help explain how the gene affects brain function and increases vulnerability for autism. The results of this innovative brain imaging study are described in an article in the groundbreaking neuroscience journal Brain Connectivity, a bimonthly peer-reviewed publication from Mary Ann Liebert, Inc. The article is available free online at the Brain Connectivity website.
"This is one of the first papers demonstrating a linkage between a particular gene variant and changes in brain structure and connectivity in carriers of that gene," says Christopher Pawela, PhD, Co-Editor-in-Chief and Assistant Professor, Medical College of Wisconsin. "This work could lead to the creation of...
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What is IMAGING GENETICS?
Paul Thompson, Ph.D.
is the study of how individual genetic differences lead to differences in brain wiring, structure, and intellectual function. Here at the Imaging Genetics Center, led by Paul Thompson, we investigate how genes and environment affect the brain. We co-founded a worldwide imaging genetics consortium, called the ENIGMA
Consortium, which is making rapid progress discovering genetic variants that affect brain integrity. ENIGMA recently performed the largest brain imaging study in the world - bringing together 207 co-authors, from 125 institutions, to analyze genome-wide scans and MRI scans from 21,151 people. We also direct several mathematical and technical projects to improve methods to understand how gene networks affect the brain.
Latest News Articles
Gene Makes People Fat, Raises Alzheimer's risk
April 20, 2010
A variant of an obesity gene carried by more than a third of the U.S. population also reduces brain volume, raising carriers' risk of Alzheimer's disease, U.S. researchers said on Monday.
People with a specific variant of the fat mass and...
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AIDS Inflicts Specific Pattern of Brain Damage
October 10, 2005
A new UCLA/University of Pittsburgh imaging study for the first time shows the selective pattern of destruction inflicted by AIDS on brain regions that control motor, language and sensory functions. High-resolution 3-D color scans created from magnetic resonance images (MRI)...
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First 3D-map shows how Alzheimer's disease engulfs the brain...
Connectomics is the study of the brain's wiring, or connectivity patterns.
International team discovers new genes that shape brain's size, intelligence...
Supercomputing approaches to map patterns of brain structure and function...
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume...
Thinning of the cerebral cortex visualized in HIV/AIDS patients.
Brain wiring is affected in people carrying the autism risk gene...
Researchers map how Schizophrenia
engulfs teen brains.
Pattern of brain tissue loss in methamphetamine users...